Clinical assessment of patients with acromegaly

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منابع مشابه

The Combination Therapy with Bromocriptine and Cyproheptadine in Patients with Acromegaly

The therapeutic efficacy of the combination of cyproheptadine and bromocriptine was studied in 15 patients with active acromegaly showing incomplete GH suppression in response to bromocriptine therapy alone. The mean basal plasma GH was 31.3±5.5 µg/L, and it decreased to 19.0±3.9 µg/L during the single bromocriptine therapy (10-20 mg for 2 to 21 months). When cyproheptadine (12 to 16 mg for 8 t...

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Clinical importance of achieving biochemical control with medical therapy in adult patients with acromegaly

In acromegaly, achieving biochemical control (growth hormone [GH] level <1.0 ng/mL and age- and sex-normalized levels of insulin-like growth factor 1 [IGF-1]) through timely diagnosis and appropriate treatment provides an opportunity to improve patient outcomes. Diagnosis of acromegaly is challenging because it is rooted in observing subtle clinical manifestations, and it is typical for acromeg...

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Follow-up of pituitary tumor volume in patients with acromegaly treated with pegvisomant in clinical trials.

OBJECTIVE We examined pituitary tumor volumes in patients treated with pegvisomant for 18 months or longer, and in whom the tumors were monitored for at least 3 years. We present details on 9 of 304 patients in clinical trials with pegvisomant who experienced tumor growth within the first year of treatment. METHOD Magnetic resonance images prior to start of pegvisomant and at last follow-up w...

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ژورنال

عنوان ژورنال: Journal of Research in Medical Sciences

سال: 2018

ISSN: 1735-1995

DOI: 10.4103/jrms.jrms_139_17